Science fiction comics in general usually have reptilian characters, so check out Fiction House's Planet Comics.
Centaur Comics' Amazing Man Comics #5-13 had a feature called Chuck Hardy that had the characters running into strange creatures.
Basil Wolverton did some sci-fi series, Spacehawk for Target Comics #5-34 (Novelty), Space Patrol for Amazing Mystery Funnies v2 #12, 19, 21-24 (Centaur) and Meteor Martin for Amazing Man Comics #25 & 26 (Centaur).
There's probably a few reptilians in some of those books.